Principles and Methods of Comparative Effectiveness Research

Course Description: Comparative effectiveness research (CER) is the conduct and synthesis of research comparing the benefits and harms of different interventions and strategies to prevent, diagnose, treat, and monitor health conditions in “real world” settings. It is a priority for the physical and economic health of the nation. This course will provide an introduction to CER and methods for conducting CER. The course will cover four areas of research methodology:

  • Design and Analysis of Randomized Clinical Trials
  • Design and Analysis of Observational Studies and Large Datasets
  • Research Synthesis, Systematic reviews, and Meta-analysis
  • Economic Evaluations, Modeling, and Health Policy

Course Learning Objectives:

  1. Introduction to the principles of CER
  2. Familiarity with key areas of research methodology needed to conduct or collaborate in CER

Target Audience: Junior faculty, clinical fellows, postdoctoral fellows, and graduate students who are pursuing, or have an interest in pursuing, comparative effectiveness research.

Minimum Recommended Prerequisites: Familiarity with research methodology, and a course in introductory statistics.